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Grape Seed Extract

grape seed extract antioxidant liquid supplement

Grape Seed Extract

Grape seeds are rich in antioxidants and oligomeric proanthroyanidin complexes (OPCs) that confer its health benefits. The grape seed extract (GSE) is derived from the seeds, pulp and white membranes of a grape fruit.  GSE is made by mixing grape fruit seeds and pulp into a highly acidic liquid. The health benefit effects of the extract were discovered by Jacob Harich an American immunologist in the year 1972. GSE encompasses a mixture of flavonoids linoleic acid, vitamin E and phenolic procyanidins. However, the most active agents of the GSE are the Oligomeric procyanidins (OPCS) or polyphenols. All these are important in protection of the blood vessels and cells from damage. Action on the blood vessels helps maintain an optimal blood pressure. Also, dilates the blood vessels thus reducing pressure.  On the other hand, OPCs play a key role in the counteraction of free radicals produced in the body due to their antioxidative property. They also inhibit lipid peroxidation courtesy of the OPCs. This is essential in maintaining a good health and longevity as it prevents premature aging.

Notably, OPCs also play an immune-supportive role as they may create a health inflammation response and prevent body’s invasion by foreign bodies that may weaken the immune system. Resveratrol present in the extract is responsible for the function as it may reduce inflammation response. Additionally, compounds known as polyphenols namely, limonoids and naringenin present in GSE   are responsible for enhancing the immune system. It also aids in reducing swelling as a result of injuries.  The ability of GSE extract to potentiate vitamin C activity also contributes to its immune-supportive function.

Another role of GSE is that it improves the health of the skin as it acts as an alpha hydroxyl acid compounds that are easily absorbed by the skin. Polyphenols are the compounds responsible for improvement in the skin elasticity as they are excellent binders of collagen fibers thus help improve the condition of connective tissues and thus generally maintaining the elasticity of skin, joints, arteries, and other connective tissues. Additionally, polyphenols are responsible for the radical scavenging ability. These neutralize the harmful singlet oxygen radicals in the body thus inhibiting unwanted inflammation and damage to the cells (Mielnik et al., 2006). Inhibit platelet aggregation thus preventing formation of clots. The flavonoids which are the most common group of polyphenolic compounds in grapes are responsible for counteracting the LDL molecules in the body thus contributing to good vascular health as it prevents clogging in vessels especially arteries.

OPCs in grape seed extract also protect the body cells from damage and unregulated multiplication through the antioxidative effect.  This also reduces oxidative stress and preserves mitochondrial function to facilitate energy production by the body cells. It also boosts the wound healing process making it heal faster and reducing scar formation. According to research, proanthocyanidin a type of polypehnol is quickens the wound healing due to its antioxidant property. Additionally, the alpha hydroxyl acid component of GSE improves the moisture barrier of the skin cells aiding in the regeneration process. The cells are able to retain enough moisture for a fresh appearance.

Grape seed extract also contains high levels of procyanadin dimmers that inhibit the enzyme aromatase to regulate cell growth hence normal growth and development.  It also improves flexibility in joints, blood vessels and body tissues and organs such as the heart. Animal studies have shown that grape seed extract is important for maintaining bone strength. It improves bone formation and strength that helps regulate skeletal growth.

Lastly, GSE has the ability to relax blood vessels thus enabling the control of blood pressure.  This function is facilitated by the presence of high concentrations of oligomeric procyanidins in the grape seed extract that stimulate the relaxation of arteries thus controlling the blood pressure. This also confers preventive and therapeutic function in maintenance of cognitive function as blood flow to the brain is increased.

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MSM (Methylsulfonylmethane)

MSM (Methylsulfonylmethane)

Dr. Stanley Jacob and Dr. Robert Herschler, chemists with the pulp and paper plant Crown Zellerbach Corporation, were asked to find a use for lignin, one of the primary waste products of the plant. Oxidation of lignin in a reactor was shown to result in the formation of DMSO (Dimethylsulfoxide), a natural, organic form of sulfur. Oxidation of DMSO was found to produce MSM, a much more stable, organic sulfur compound with medicinal properties.

MSM is found in protein-rich foods such as eggs, meat, poultry, fish, and legumes. Other good sources include garlic, onions, Brussels sprouts, asparagus, kale, and wheat germ. It enhances the activity of cortisol, a natural anti-inflammatory hormone produced by the body. MSM improves the permeability of cell membranes, which improves the uptake of nutrients and many vitamins and the elimination of waste products and excess cellular fluids. MSM dilates blood vessels, enhancing the blood circulation which also helps to eliminate waste products from the body and speeds up healing. MSM is a muscle relaxant. This is an important and often overlooked benefit of MSM.

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Product Name: Methylsulfonylmethane (MSM)  

Test Type: Identification and Purity

Country of Origin: China

  Test Method: USP
Test Type: Microbiology  

Yeast & Mold

Test Method: USP
Test Type: Chemical Lead
Test Method: USP

MSM (Methylsulfonylmethane) Source


MSM (Methylsulfonylmethane) Beijing, China

Office Phone: 1-800-216-3231
Office Fax: 1-423-881-3214 

Office Hours
Monday – Thursday
8:00 am – 5:00 pm cst

Mailing Address
Buried Treasure
PO Box 949
Pikeville, TN 37367


The Council for Responsible Nutrition   Producer of SOHO EXPO a Natural Products Industry Trade Show

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Andographis Immune function

The immune system is the body’s natural defense system. However, at times challenges to the immune system may call for some extra nutritional support. Andrographis paniculata, a common name in Ayurveda medicine is one such immune enhancing herb that confers immunomodulating properties that help stimulate the immune system (Okhuarobo eta l.,2014).

The plants active component, andrographolide is a potent immune system stimulant that works by enhancing cell-mediated immune response. For instance, research shows that natural killer cell mediated target cell lysis is enhanced by the administration of andrographis paniculata extract. Besides, andrographolides promote the production of white blood cells, interferon release and enhance the protective function of the lymphatic system. The macrophages and antibodies   produced scavenge for invaders through antibody dependent cell-mediated cytoxicity thus restoring immunity (S. (2013, August 01). They also, reduce the levels of pro-inflammatory cytokines such as IL-1beta, IL-6, GM-CSF and TNF-alpha (Sheeja & Kuttan, 2010). Therefore, it is evident that Andrographis paniculata’s immune stimulating ability confer its beneficial biological properties.

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Thyme for natural health and wellness


An aromatic herb in the mint family, thyme grows to a height of fifteen inches (about 40 cm), with small rounded leaves and pink flowers on woody stems. Today the plant is common throughout North America, but it originated in the southern Mediterranean. Experts in language tell us that thyme’s name was derived from the Greek word thumus, or courage. In Medieval times, knights wore sprigs of thyme on their armor as a sign of courage. The scent of thyme was thought to give them strength in the midst of battle.

The interesting health benefits of thyme include its ability to relieve stress.  With one of the highest antioxidant concentrations in any herb, thyme has been praised for thousands of years as an overall health booster. The phenolic antioxidants found in thyme, including lutein, zeaxanthin, and thymonin contribute to neutralizing and eliminating free radicals throughout the body.