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Vitamin B12

Vitamin B12

Vitamin B12 is a water-soluble vitamin   that exists in several cobalt containing forms .These compounds showing vitamin B12 activity are known as cobalamines. It has a complex structure made up of   a tetrayrrole ring system called a corrin ring with a central cobalt atom. An R group is attached to the central cobalt atom which gives the various forms of vitamin B12.  A cyanide R group forms cyanocobalamin, hydroxyl R group forms hydroxyl cobalamin, a methyl R group forms methyl cobalamine, and a deoxyadenosine R group forms deoxyadenosyl cobalamin. All these exhibit vitamin B12 activity. Mammals are unable to synthesize cobalamins and as such are obtained from the diet. Any excess amount is usually excreted in urine hence vitamin B 12 toxicity is rare.

Vitamin B12 functions as a prosthetic group or coenzyme.  Humans and other higher animals require vitamin B 12   for two enzymes; methionine synthase and methymalonyl-coA mutase (MCM).  For instance, methyl cobalamine is involved in the synthesis of purines and pyrimidines by methionine synthase. Another function conferred by methionine synthetase is   the formation of phospholipids and neurotransmitters hence enabling proper functioning of the neurological system. Its role in the formation of myelin also aids in the normal functioning of the brain and the nervous system. Therefore, a deficiency in vitamin B12 results in neurological disturbances or paraesthesia or in extreme cases degeneration of the spinal cord.

Vitamin B 12 is also essential for the rapid DNA production during the process of cell division.  This plays a crucial in the synthesis of blood cells in the bone marrow where the cells divide rapidly.  In absence of B12, the synthesis of DNA is interfered with and as a result abnormal cells known as megaloblasts are produced during red blood cell formation. Therefore, vitamin B12 is essential in the formation of healthy blood cells so that they multiply and develop properly.

It also functions to lower the plasma concentration of homocsyteine that is crucial for effective cardiac function.  Vitamin B 12 is crucial coenzyme in the conversion of homocsyteine into methionine.  Elevated levels are a risk factor for improper cardiac function as it promotes atherosclerosis.

Vitamin B 12 plays a role in cellular energy production. It is involved in the metabolism as it is involved in fatty acid synthesis hence enabling the release of energy by the body.  In addition, it is involved the absorption of folic acid that is required for effective neurological function.  Vitamin B 12 also plays a role in the normal structure and functioning of nerves.

Vitamin B 12 deficiency is common due to the limited dietary intake of animal foods. Research in the United States depicts that about 1.5-15% of the population are diagnosed with vitamin B12 deficiency. Vitamin B12 deficiency affects the bone marrow, intestinal tract, and the neurological system.  The deficiency could be as a result of inadequate intake especially in vegetarians or lack of intrinsic factor a substance that aids its absorption. Some drugs such as colchicine, salicylates, and neomycin can also induce vitamin B12 deficiency by interacting with intrinsic factor.  This leads to the development of pernicious anemia.  Above all, prolonged alcohol consumption can also impair the absorption of vitamin B12.  This affects the hematopoietic system, the gastrointestinal system, and nervous system.

The daily requirement  of vitamin B12  in adults is up to 3-4 micrograms per day. Vitamin B12 is mainly extracted from animal sources such as kidney, liver, brain, meat, fish, and eggs. The fact that it is absent from animal sources makes vegetarians vulnerable to vitamin B12 deficiency.

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Vitamin B2 Riboflavin

Riboflavin: Vitamin B2

Also known as riboflavin it is present in plants, bacteria.  However, it is absent in vertebrates. It is a colored micronutrient that is easily absorbed to maintain proper functioning of tissues and organs. The word riboflavin is derived from “Ribose” meaning sugar whose reduced form is ribitol and “flavin’ which is a ring moiety that is responsible for the yellow color of the oxidized molecule of vitamin B2.

Its structure is made up of a heterocyclic isoalloxazine ring and a sugar alcohol known as ribitol. Although sensitive to light and alkali it is stable against heat and acidic medium. The active forms of riboflavin are flavin mononucleotide (FMN) and flavin adenine mononucleotide (FAD).These forms the prosthetic groups of various enzymes known as flavoenzymes. The flavoenzymes play a key role in catalyzing oxidation-reduction reactions by acting as carriers of hydrogen atoms. On the other hand, the isoalloxazine rings participates in the oxidation reduction of substrates .The isoalloxazine ring is reduced to FMNH2 and FADH2.

Just like other B vitamins riboflavin is crucial for the normal physiologic processes.  It is necessary for normal development, growth, reproduction, lactation, physical performance and general well-being. Vitamin B 2 being a precursor of essential coenzymes FAD and FMN takes  part in a range of essential biochemical redox reactions, especially in those that yield high energy. It is involved in various metabolic reactions and takes part in the mitochondrial electron transport chain to produce energy.

Riboflavin is also required for the synthesis and repair of nucleic acids, namely RNA and DNA. As such, it promotes growth and fertility since it supports reproduction of the various body cells including sex cells. It also promotes good vision in combination with vitamin A.  In addition, it is important for the maintenance of a healthy skin, nails and hair.

Riboflavin also plays a crucial role in neutralizing free radicals as it is involved in the regeneration of glutathione, the body’s main defense system against free radical damage. It is these free radicals that damage DNA and cells. Riboflavin is also necessary for folic acid activation. It also activates pyridoxine. Additionally, it plays a role in the conversion of tryptophan to niacin in the liver.

Riboflavin is also involved in the metabolism of fats, ketone bodies carbohydrates and proteins to produce energy. Therefore, riboflavin is important for stimulating growth by providing nutrients from the metabolized macromolecules. Being the central component of various co-factors such as flavin adenine mononucleotide and flavin mononucleotide it plays a key role in catalyzing redox reactions in the body to produce energy. As such, it is commonly known as one of the energy vitamins.

Riboflavin deficiency known as ariboflavinosis can occur as a result of aging and reduced efficiency in absorption.  Deficiency normally occurs in combination with deficiency of other vitamins. It is characterized by cracked and red lips, inflammation of the lining of the mouth and tongue, dry scaly skin, fluid in mucous membranes, mouth ulcers, and cracks at the corners of the mouth.

The recommended daily allowance in the United States is 1.3 mg for males and 1.1 mg for females. It is best absorbed when taken between meals, since just like thiamine; riboflavin requirement also depends on the carbohydrate intake. Rich sources of vitamin B2 include cereals, meat , fish, fish and dark-green vegetables. Milk and other dairy products fortified with B2 are the largest dietary contributors in the western population. The body does not have a mechanism for storing riboflavin and as such must be replenished on a regular basis through dietary intake. There is no toxicity at higher intake as it is excreted in urine.

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Ginkgo Biloba

ginkgo biloba medicinal herbs for focus and memory

Ginkgo Biloba

Also known as maidenhair, Gingko biloba is an ancient plant that is native to Asia and Africa but also thrives in parts of Europe. Typically, Ginkgo biloba extract (GBE) is obtained from the dried leaves of the plant only as the seeds are said to be toxic according to the University Of Maryland Medical Center. Leaves of the gingko tree contain up to 40 active components.  However, the extracts main health benefits due to the presence of two beneficial constituents including flavonoids those give it antioxidant properties and terpenoids. Flavonoids are plant based anti-oxidants.  They protect the various body cells from damage. Terpenoids such as ginkgolides on the hand have a beneficial effect on vascular health as   it dilates blood vessels increasing blood flow thus improving general circulation in the body, especially to the vital organs such as the brain, heart and kidneys. It also counteracts platelet aggregation by making them less sticky.  Some of the biological effects of ginkgo biloba leave extract include the scavenging of free radicals, reducing oxidative stresses, reducing neural damage, reduces platelet aggregation and minimizes inflammation.

The plant extract may create an effective inflammation response hence providing an immunosupportive function. Its ability to improve circulation reinforces the detoxification process and supports its immune function. The flavonoids in the Ginkgo biloba leaf extract inhibit the cyclo-oxygenase and lipooxygenase systems that are involved in the metabolism of arachidonic acid. Besides, the flavonoid component is also said to reduce edema as a result of tissue injury and also protects against capillary fragility.

Ginkgo Biloba extract has a brain boosting effect. It facilitates improved cognitive function and boosts memory by lowering the oxidative stress and improving circulation which has a cerebral enhancing effect. There are various mechanism of action, one of them being the ability to influence the uptake of glucose by brain cells, which further improves nervous transmission which is responsible for the execution of various body processes such as memory. Its vasodilative effect also increases blood flow to the brain.  Its ability to neutralize free radicals also enables it to neutralize any damage to the neurons and brain cells. Therefore GBE has a positive effect on learning and memory processes.

GBE has the ability to boost blood circulation by stimulating both increased peripheral and cerebral flow. It improves circulation by inducing vasodilatation and making the platelets less sticky. It also increases red blood cell deformidability and decreases their aggregation as well. This results in increased red blood cell fluidity and decreases whole blood viscosity. Circulation boosting effects are also beneficial in the maintenance of vision.  The presence of flavonoids that have an antioxidant property as well as the ability to increase blood flow to the eye reduces complication of the retina that often results to macular degeneration. Specifically,   gingko may help preserve vision in age-related macular degeneration that ranks as the number one cause of blindness in the United States.

Gingko extract offers protection against oxidative cell or DNA damage caused by free radicals that confers its antioxidant properties.  Components in ginkgo leaves that function as antioxidants include, terpenoids, phytochemicals and flavonoids.  Its potent antioxidant function protects against reversible cell damage. It helps counteract free radicals in the brain, eyes, cardiovascular system and in the nerves. This helps the boosts ones health and longevity as the free radicals tend to build up with age posing a danger to the cells and genetic material as well.

Indeed, gingko plays a key role in the normal functioning of the body. It contains the lipid phospahtidylserine that is vital for the normal functioning of all the body cells.  It is mainly abundant in the brain thus contributing to gingko’s therapeutic effect on the brain. Lastly, ginkgo extract has role in management of anxiety and stress as it helps suppress the levels of corstisol in the body which is the main stress hormone in the body. Animal studies have shown that GBE inhibits monoamine oxidase that regulates biogenic amines in the brain. Therefore, exposure to the plant extract elevates the brain concentrations of serotonin, norepinephrine and other biogenic amines.

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Active!!

active

Being active is not just for the young. You can feel great and enjoy the things you love to do by keeping a healthy lifestyle. Buried Treasure has developed a number of fast to act liquid nutrients that help your body with energy, focus and antioxidants. Work and play can both be better with a healthy lifestyle!

      

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Stay Active

vitality

Staying active as you age is important to how you feel and the strength your body has for the actives you enjoy. Buried Treasure has formulated liquid nutrients to help your body get what it needs thru the days, weeks, months and years.

Check out the great liquid nutrients we have like Active 55 Plus, Stress B Gone, Joint Ease and Digestive Relief.

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Family (lifestyle)

family_02We know family is first and most precious to you. You want to ensure they grow healthy and strong with the minerals and vitamins they need. Buried Treasure has a full line of products for each member of your family from pre-natal to over 55.

Buried Treasure – “experience the liquid advantage”

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Energy to go and go and…

energyxtension_01

 

 

Get the most out of your day!! Buried Treasure Energy Xtension,

an energizing supplement that works with your body to improve endurance and increase physical and mental working capacity in a fast-acting liquid formula. Make a healthy choice to keep you going.

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VM-100 Complete

Buried Treasure VM100 Complete Daily Multivitamins and Minerals plus Antioxidants

VM-100 Complete
  • Buried Treasure VM100 Complete liquid whole food based daily nutritional supplement provides vitamins, mineral and antioxidants in a great tasting liquid for a fast absorbing complete daily supplement.

  • Buried Treasure VM100 Complete daily supplement Vitamins include Vitamin A (10,000 IU), Vitamin C (1,000 mg), Vitamin D (1200 IU), Vitamin E (400 IU), Vitamin B-1, B-2, Niacin, B-6, B-12, Methylfolate and much more.

  • Buried Treasure VM100 Complete Minerals with more than 70 plant based colloidal mineral complex including Zinc, Copper, Selenium, Chromium, Potassium, Copper, Selenium and more.

  • VM100 Complete comprehensive liquid vitamin and mineral supplement includes an herbal blend of Ginkgo, Boron, Lycopene, Grape Seed Extract, Rutin plus Citrus Bioflavonoids.

  • Buried Treasure VM100 Complete is  Vegetarian safe, No Gluten, No Wheat, Non-Dairy, No Yeast. No artificial ingredients, colors, flavors or preservatives. Buried Treasure is a USDA, FDA and cGMP facility in Pikeville, TN

 

What are the benefits?

Buried Treasure’s VM-100 is a High Potency Vitamin plus Plant-Derived Minerals Nutritional System. Rich in antioxidants, VM-100’s liquid form starts working for you faster than any tablet, capsule or softgel product. Because the digestive system becomes less effective as we age, leading to poor absorption of nutrients, highly absorbable liquid VM-100 COMPLETE is the perfect solution for all ages!

 

INGREDIENTS per serving  
Calories 20
Total Carbohydrates  5g
Sugars 4g
Vitamin A (beta-carotene) 10,000 IU
Vitamin C (ascorbic acid) 1,000 mg
Vitamin D (ergocalciferol) 1200 IU
Vitamin E (d-alpha tocopheryl) 400 IU
Vitamin B-1 (thiamin) 50 mg
Vitamin B-2 (riboflavin) 50 mg
Niacin (niacinamide) 50 mg
Vitamin B-6 (pyridoxine HCL) 50 mg
Folate (Calcium L-5 Methyltetrahydrofolate) 500 mcg
Vitamin B-12 (methylcobalamin) 1,000 mcg
Biotin 300 mcg
Pantothenic Acid 150 mg
Calcium (citrate) 100 mg
Magnesium (citrate) 50 mg
Zinc (citrate) 15 mg
Copper (gluconate) 2 mg
Manganese (citrate) 3 mg
Selenium (chelate) 100 mcg
Chromium (picolinate) 100 mcg
Potassium (citrate) 50 mg
Inositol 50 mg
Paba (para-aminobenzoic acid) 50 mg
Citrus Bioflavonoids 65 mg
(hesperidin)  
Choline Bitartrate 50 mg
Rutin 40 mg
Rosemary Extract (leaves) 30 mg
Grape Seed Extract 5 mg
Alpha Lipoic Acid 2.5 mg
Ginkgo Biloba Extract 10 mg
(leaves)  
Boron (citrate) 2 mg
Lycopene 200 mcg
70+ Plant Sourced Minerals Proprietary Blend 250 mg

Other Ingredients: Purified mountain water, white grape juice, orange juice, apple juice. natural flavor, xanthan gum, guar gum, organic citrus extract and/or citric acid, potassium sorbate (to ensure freshness), nisin (naturally ensures freshness) and polylysine (natural preservative).

 

DIRECTIONS: SHAKE WELL BEFORE EACH USE. REFRIGERATE AFTER OPENING. BEST IF USED WITHIN 45 DAYS FROM OPENING. Adults should take 2 tablespoons daily. We recommend you mix it with your favorite juice. Do not take on an empty stomach. 

 

Caution:  Pregnant and nursing women should check dosage with their healthcare professional. Keep out of reach of children.

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